Traditionally, agricultural interventions have focused on increasing food production and raising incomes to reduce malnutrition, hunger and poverty. Although this remains part of a valid approach, it is now recognized that higher levels of production and income alone have limited impact on improving nutrition. A more comprehensive approach is necessary to optimize agriculture’s contribution to good nutrition and make agriculture nutrition sensitive. Such an approach identifies constraints and opportunities to leverage agriculture for better nutrition throughout a food system, without detracting from the agricultural sector’s conventional goals. It explicitly takes nutrition outcomes into account in the design and implementation of agricultural interventions to ensure that impacts on nutrition are positive and significant.